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DJPS

Diyala Journal For Pure Science

Scientific Refereed Journal Published By College of Science - University of Diyala

 

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djps.1303.250B

Diyala Journal For Pure Sciences DJPS

ISRA Impact Factor:3.715

P- ISSN:2222-8373, E-ISSN:2518-9255

Volume 13, Issue 3, Part 1 , July. 2017

 

Study a level of TNF-α and INF-Ƴ in patients with Type I and II Diabetes Mellitus in Diayla governorate

 

Mohammed Abdul-Daim Saleh , Shahrazad Ahmed Khalaf

 

Year: 2017, Volume: 13, Issue: 3, Part: 1

 

Pages: 196-207, DOI: http://dx.doi.org/10.24237/djps.1303.250B 

 

Language: English

 

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Abstract    


  

The aim of this study was to determine a level of TNF-α and INF-Ƴ in patients with Type I and Type II Diabetes Mellitus, this cytokines measured by enzyme-linked immunosorbent assay (ELISA). A total of 70 patients and 20 healthy volunteers were included in this study, collected during the period from the beginning of August 2015 to the end of May 2016. The results showed a significant increase in the concentration of INF-Y in the serum of both types diabetes mellitus  with the control group  there were,  the level of INF-Y  in patients with type I and type II diabetes mellitus was  740.1, 738.5  pg / mL  respectively while the level in control group was 431.9 pg / mL .As well as  the results showed a significant increase in the concentration of TNF-α in the serum of both types diabetes mellitus  than control group  there were,  the level of TNF-α  in patients with type I and type II diabetes mellitus was  339.2  , 228.4  pg / mL  respectively while the level in control group was107.8  pg / ml. 

 

  Key word: Diabetes Mellitus , TNF-α , INF-Ƴ .                                         

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