Diyala Journal For Pure Science
Scientific Refereed Journal Published By College of Science - University of Diyala
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Diyala Journal For Pure Sciences DJPS
ISRA Impact Factor:3.715
P- ISSN:2222-8373, E-ISSN:2518-9255
Volume 14, Issue 4 , October . 2018
Synthesis and Characterization of Two 3,4-Dihydropyrimidinone Derivatives
Noor Raisan Ali , Mahmood Shakir Magtoof
Year: 2018, Volume: 14, Issue: 4
Pages: 170-175 , DOI: http://dx.doi.org/10.24237/djps.1404.463B
In this study we have successfully synthesis and characterization two of [3,4-dihydropyrimidin-2-(1H) ones] (1a and 1b). The compounds were synthesized by reaction of ethyl acetoacetate and aromatic aldehyde with urea in the presence of ethanol and FeCl3.6H2O with 3-5 drops of HCl at 60-65 OC. Spectral measurements (e.g. FT-IR,1H-NMR and 13C-NMR) are used to investigate the chemical structures and characterize the obtained product of synthesized compounds.
Keywords: 3,4- Dihydropyrimidine-2-(1H)-ones, Biginilli reaction.